Regulatory Watch
Mar 2026: NPR covers peptide reclassification (March 26) — mainstream audience discovers peptide market Mar 2026: 29 days post-RFK announcement: FDA has STILL not published reclassification — no Federal Register notice, no updated list Mar 2026: SAFE Drugs Act filed as H.R. 6509 — bipartisan bill would ban RUO sales of compounds identical to FDA-approved drugs Mar 2026: PolitiFact publishes peptide safety fact-check — documents gap between marketing claims and published evidence Mar 2026: Hims & Hers vendor profile added — NYSE-listed telehealth company building peptide manufacturing in California Mar 2026: 30+ clinic websites publishing reclassification articles — all financially conflicted, none independent Mar 2026: BREAKING: Peptide Sciences shuts down operations (March 6) — largest grey-market vendor gone Mar 2026: Finnrick data: Peptide Sciences BPC-157 scored A, but retatrutide scored E with counterfeit flagged across 37 samples Mar 2026: MMM Online: 'Get ready for the peptides gold rush' — pharma trade media covers market explosion Mar 2026: Jay Campbell: 'Federal government has decided RUO peptide manufacturing can no longer sell injectable peptides' Mar 2026: Grips Intelligence: Peptide Sciences was doing $7.4M/month in sales before shutdown — market vacuum now open Mar 2026: All American Peptide owners plead guilty — $3M+ forfeitures. Tailor Made Compounding: $1.79M forfeiture. June 2025: FDA raids Amino Asylum warehouse; website goes offline, operations cease Feb 2025: FDA declares semaglutide shortage resolved — compounding exception ends Sept 2025: FDA issues 50+ warning letters to GLP-1 compounders; DOJ involvement confirmed Nov 2025: Alabama obtains TRO against GLP-1 distributors — first state-level injunctive relief Sept 2023: FDA moves BPC-157, TB-500, and 15 other peptides to Category 2 — compounding prohibited Dec 2024: PCAC votes against allowing compounding of ipamorelin, MK-677, CJC-1295, AOD-9604 Jan 2025: FDA eliminates Category 2/3 system; prohibited substances remain prohibited Feb 2026: STAT News: 35 of 36 BPC-157 studies are animal-only from single lab with undisclosed conflicts 2025: Chinese peptide imports to US double to $328M; online peptide advertising up 678% since 2022 Mar 2026: NPR covers peptide reclassification (March 26) — mainstream audience discovers peptide market Mar 2026: 29 days post-RFK announcement: FDA has STILL not published reclassification — no Federal Register notice, no updated list Mar 2026: SAFE Drugs Act filed as H.R. 6509 — bipartisan bill would ban RUO sales of compounds identical to FDA-approved drugs Mar 2026: PolitiFact publishes peptide safety fact-check — documents gap between marketing claims and published evidence Mar 2026: Hims & Hers vendor profile added — NYSE-listed telehealth company building peptide manufacturing in California Mar 2026: 30+ clinic websites publishing reclassification articles — all financially conflicted, none independent Mar 2026: BREAKING: Peptide Sciences shuts down operations (March 6) — largest grey-market vendor gone Mar 2026: Finnrick data: Peptide Sciences BPC-157 scored A, but retatrutide scored E with counterfeit flagged across 37 samples Mar 2026: MMM Online: 'Get ready for the peptides gold rush' — pharma trade media covers market explosion Mar 2026: Jay Campbell: 'Federal government has decided RUO peptide manufacturing can no longer sell injectable peptides' Mar 2026: Grips Intelligence: Peptide Sciences was doing $7.4M/month in sales before shutdown — market vacuum now open Mar 2026: All American Peptide owners plead guilty — $3M+ forfeitures. Tailor Made Compounding: $1.79M forfeiture. June 2025: FDA raids Amino Asylum warehouse; website goes offline, operations cease Feb 2025: FDA declares semaglutide shortage resolved — compounding exception ends Sept 2025: FDA issues 50+ warning letters to GLP-1 compounders; DOJ involvement confirmed Nov 2025: Alabama obtains TRO against GLP-1 distributors — first state-level injunctive relief Sept 2023: FDA moves BPC-157, TB-500, and 15 other peptides to Category 2 — compounding prohibited Dec 2024: PCAC votes against allowing compounding of ipamorelin, MK-677, CJC-1295, AOD-9604 Jan 2025: FDA eliminates Category 2/3 system; prohibited substances remain prohibited Feb 2026: STAT News: 35 of 36 BPC-157 studies are animal-only from single lab with undisclosed conflicts 2025: Chinese peptide imports to US double to $328M; online peptide advertising up 678% since 2022

Science.bio (Closed)

science.bio ↗
Founded: 2019 (originally IRC.bio, 2016) HQ: United States Last reviewed: February 20, 2026
A-
Overall Grade
Transparency 95/100
Testing 90/100
Pricing 70/100
Reputation 90/100
Compliance 40/100
Publishes COA Yes
Third-Party Testing Yes
FDA Warning Letters 0
Product Types lyophilized-powder, solution, capsule

Company Overview

Science.bio operated from 2019 to approximately early 2026, with significant interruptions. Originally launched as IRC.bio in 2016 (shut down November 2018 due to SARM regulations), it relaunched as Science.bio in April 2019. The company permanently closed in February 2022, briefly reopened in May 2023, and appears to have finally shut down by January 2026.

This profile is included for historical reference — Science.bio was widely considered the gold standard for research chemical quality control, and its closure created a significant market gap that has not been adequately filled.

⚠️ Status: CLOSED — Do Not Attempt to Purchase

Science.bio is no longer operational. Any websites claiming to be Science.bio should be treated with extreme caution as potential impersonators. A sister site, Botany.bio, may still operate.

Why Science.bio Was the Gold Standard

Science.bio set the bar for transparency and quality in the research chemical market:

  • Extensive lab reports: Every product batch had full analytical documentation including HPLC chromatograms, mass spectrometry data, and identity confirmation
  • Batch tracking: Consumers could verify specific batch numbers against published lab reports
  • ISO-compliant manufacturing: Production processes followed pharmaceutical-grade standards
  • Named testing laboratories: The labs performing analysis were identified, allowing independent verification
  • Multiple testimonials from analytical chemists and researchers: Professional scientists validated their quality practices

Scoring Rationale (Historical)

Transparency: 95/100 — Arguably the most transparent research chemical vendor ever to operate. Full lab documentation, named labs, batch tracking.

Testing: 90/100 — Comprehensive testing program validated by independent professionals.

Pricing: 70/100 — Not the cheapest, but pricing reflected the genuine quality infrastructure behind the products.

Reputation: 90/100 — Universally positive reputation in the research chemical community. Multiple independent recommendations from analytical professionals.

Compliance: 40/100 — Despite exemplary quality practices, Science.bio operated in the “research use only” market that the FDA considers legally problematic. Their repeated closures and reopenings likely reflect the regulatory pressure on this business model.

Why This Matters for the Current Market

Science.bio’s closure demonstrates a fundamental tension in the peptide market: the vendor with the best quality practices was ultimately unable to sustain operations, likely due to regulatory pressure. Meanwhile, vendors with far lower quality standards continue to operate. This creates a perverse incentive structure where transparency and quality investment make a vendor more visible to regulators, while opacity and minimal quality practices allow continued operation.

For consumers, Science.bio’s absence means the benchmark for quality has been removed from the market. No current vendor has replicated their level of transparency and documentation.

The Bottom Line

Science.bio showed what good looked like in the research chemical market — and couldn’t make it work long-term. We include this profile to establish what quality transparency should look like, so consumers can evaluate current vendors against a concrete standard rather than an abstract ideal. If a current vendor doesn’t approach Science.bio’s level of documentation and verification, that’s worth knowing.