Regulatory Watch
June 2025: FDA raids Amino Asylum warehouse; website goes offline, operations cease Feb 2025: FDA declares semaglutide shortage resolved — compounding exception ends Sept 2025: FDA issues 50+ warning letters to GLP-1 compounders; DOJ involvement confirmed Nov 2025: Alabama obtains TRO against GLP-1 distributors — first state-level injunctive relief Sept 2023: FDA moves BPC-157, TB-500, and 15 other peptides to Category 2 — compounding prohibited Dec 2024: PCAC votes against allowing compounding of ipamorelin, MK-677, CJC-1295, AOD-9604 Jan 2025: FDA eliminates Category 2/3 system; prohibited substances remain prohibited Feb 2026: STAT News: 35 of 36 BPC-157 studies are animal-only from single lab with undisclosed conflicts 2025: Chinese peptide imports to US double to $328M; online peptide advertising up 678% since 2022 June 2025: FDA raids Amino Asylum warehouse; website goes offline, operations cease Feb 2025: FDA declares semaglutide shortage resolved — compounding exception ends Sept 2025: FDA issues 50+ warning letters to GLP-1 compounders; DOJ involvement confirmed Nov 2025: Alabama obtains TRO against GLP-1 distributors — first state-level injunctive relief Sept 2023: FDA moves BPC-157, TB-500, and 15 other peptides to Category 2 — compounding prohibited Dec 2024: PCAC votes against allowing compounding of ipamorelin, MK-677, CJC-1295, AOD-9604 Jan 2025: FDA eliminates Category 2/3 system; prohibited substances remain prohibited Feb 2026: STAT News: 35 of 36 BPC-157 studies are animal-only from single lab with undisclosed conflicts 2025: Chinese peptide imports to US double to $328M; online peptide advertising up 678% since 2022

Reconstitution Calculator

Lyophilized (freeze-dried) peptides must be mixed with bacteriostatic water before use. The amount of water you add determines the concentration.

Concentration: 25 mcg per unit
Units to draw: 10 units
Volume: 0.10 mL
The Formula: Concentration (mcg/unit) = Peptide Amount (mcg) / Water Added (units)
100 units = 1 mL on a standard insulin syringe

Common Reconstitution Examples

BPC-157 (5mg vial)

Water Added Concentration 250 mcg dose 500 mcg dose
1 mL 50 mcg/unit 5 units 10 units
2 mL 25 mcg/unit 10 units 20 units
3 mL 16.7 mcg/unit 15 units 30 units

TB-500 (5mg vial)

Water Added Concentration 250 mcg dose 500 mcg dose
1 mL 50 mcg/unit 50 units (2.5mg) 100 units (full syringe)
2 mL 25 mcg/unit 100 units (2.5mg) Use 2 syringes

Ipamorelin (5mg vial)

Water Added Concentration 250 mcg dose 500 mcg dose
2 mL 25 mcg/unit 8 units (200mcg) 12 units (300mcg)
2.5 mL 20 mcg/unit 10 units (200mcg) 15 units (300mcg)

Semaglutide (5mg vial)

Water Added Concentration 250 mcg dose 500 mcg dose
2 mL 25 mcg/unit 10 units (0.25mg) 20 units (0.5mg)
2.5 mL 20 mcg/unit 12.5 units (0.25mg) 25 units (0.5mg)

Research Dosage Reference

Critical Disclaimer: The dosages listed below are compiled from published preclinical research, anecdotal community reports, and (where applicable) approved pharmaceutical labeling. They are NOT medical recommendations. PeptideExaminer does not recommend self-administration of any research peptide. These figures are provided as educational reference only.

Recovery & Healing Peptides

Peptide Common Dose Frequency Route Notes
BPC-157 200-500 mcg 1-2x daily SubQ or oral Lower end for maintenance; higher for acute injury protocols
TB-500 2-2.5 mg 2x/week (loading); 1x/week (maintenance) SubQ Loading phase typically 4-6 weeks
GHK-Cu 1-2 mg 1x daily SubQ Also available topically (1-3% cream)
KPV 200-500 mcg 1-2x daily SubQ or oral Oral may be effective for gut-specific applications

Growth Hormone Secretagogues

Peptide Common Dose Frequency Route Notes
Ipamorelin 200-300 mcg 2-3x daily SubQ Best before bed and/or post-workout
CJC-1295 (no DAC) 100-200 mcg 2-3x daily SubQ Typically paired with ipamorelin
CJC-1295 (with DAC) 1-2 mg 1-2x/week SubQ Long half-life; do not combine with no-DAC version

Anti-Aging

Peptide Common Dose Frequency Route Notes
Epithalon 5-10 mg Daily for 10-20 day cycles SubQ Typically cycled: 10-20 days on, 4-6 months off

Sexual Health

Peptide Common Dose Frequency Route Notes
PT-141 (Bremelanotide) 1.75 mg (FDA-approved) On-demand, max 1x/day SubQ Max 8 doses/month per FDA label; nausea is common

Metabolic / Weight Loss

Peptide Common Dose Frequency Route Notes
Semaglutide (Wegovy) 0.25 mg starting 1x/week SubQ Titrate up to 2.4 mg over weeks
Tirzepatide (Zepbound) 2.5 mg starting 1x/week SubQ Titrate up to 15 mg over weeks

Syringe Reading Guide

100-Unit (1 mL)

  • Each small line = 1 unit (0.01 mL)
  • Each numbered line = 10 units (0.1 mL)
  • Full syringe = 100 units (1 mL)

Standard size, good for most doses

50-Unit (0.5 mL)

  • Each small line = 1 unit (0.01 mL)
  • Each numbered line = 5 units (0.05 mL)
  • Full syringe = 50 units (0.5 mL)

Better accuracy for small doses

30-Unit (0.3 mL)

  • Each small line = 0.5 units (0.005 mL)
  • More precise markings
  • Full syringe = 30 units (0.3 mL)

Most precise for very small doses

Tip: For doses under 10 units, use a 30-unit syringe for better accuracy. For doses over 50 units, use a 100-unit syringe.

Reconstitution Best Practices

What You Need

  • Lyophilized peptide vial
  • Bacteriostatic water (BAC water) — NOT sterile water, NOT saline
  • Insulin syringes (100-unit, 1 mL)
  • Alcohol swabs
  • Clean workspace

Step-by-Step

  1. Clean: Wipe the tops of both the peptide vial and BAC water vial with alcohol swabs
  2. Draw water: Using an insulin syringe, draw your chosen amount of BAC water
  3. Add slowly: Insert the needle into the peptide vial and let the water run down the SIDE of the vial — do NOT squirt directly onto the powder
  4. Don't shake: Gently roll the vial between your palms or let it sit in the refrigerator for 15-30 minutes. Shaking can denature the peptide.
  5. Check clarity: The solution should be clear and colorless. Cloudiness or particles indicate contamination or degradation — discard.
  6. Store: Refrigerate at 2-8 C. Use within 2-4 weeks.

Common Mistakes

  • Using too little water: Creates concentrated solutions where small syringe errors = large dose errors
  • Using too much water: Creates dilute solutions requiring large injection volumes
  • Squirting water onto powder: Can damage peptide through mechanical stress
  • Shaking vigorously: Denatures peptides
  • Using sterile water instead of BAC water: No preservative = bacterial growth risk
  • Not swabbing vial tops: Introduces contaminants
  • Reusing needles: Dulls the needle and introduces bacteria

PeptideExaminer provides this reference for educational purposes only. We strongly recommend working with a knowledgeable healthcare provider for any peptide protocol. We do not sell peptides or encourage self-administration.