Regulatory Watch
June 2025: FDA raids Amino Asylum warehouse; website goes offline, operations cease Feb 2025: FDA declares semaglutide shortage resolved — compounding exception ends Sept 2025: FDA issues 50+ warning letters to GLP-1 compounders; DOJ involvement confirmed Nov 2025: Alabama obtains TRO against GLP-1 distributors — first state-level injunctive relief Sept 2023: FDA moves BPC-157, TB-500, and 15 other peptides to Category 2 — compounding prohibited Dec 2024: PCAC votes against allowing compounding of ipamorelin, MK-677, CJC-1295, AOD-9604 Jan 2025: FDA eliminates Category 2/3 system; prohibited substances remain prohibited Feb 2026: STAT News: 35 of 36 BPC-157 studies are animal-only from single lab with undisclosed conflicts 2025: Chinese peptide imports to US double to $328M; online peptide advertising up 678% since 2022 June 2025: FDA raids Amino Asylum warehouse; website goes offline, operations cease Feb 2025: FDA declares semaglutide shortage resolved — compounding exception ends Sept 2025: FDA issues 50+ warning letters to GLP-1 compounders; DOJ involvement confirmed Nov 2025: Alabama obtains TRO against GLP-1 distributors — first state-level injunctive relief Sept 2023: FDA moves BPC-157, TB-500, and 15 other peptides to Category 2 — compounding prohibited Dec 2024: PCAC votes against allowing compounding of ipamorelin, MK-677, CJC-1295, AOD-9604 Jan 2025: FDA eliminates Category 2/3 system; prohibited substances remain prohibited Feb 2026: STAT News: 35 of 36 BPC-157 studies are animal-only from single lab with undisclosed conflicts 2025: Chinese peptide imports to US double to $328M; online peptide advertising up 678% since 2022

Integrative Peptides

integrativepeptides.com ↗
Founded: 2018 HQ: Hudson, Michigan Last reviewed: February 20, 2026
C+
Overall Grade
Transparency 40/100
Testing 55/100
Pricing 35/100
Reputation 60/100
Compliance 45/100
Publishes COA No
Third-Party Testing Yes
FDA Warning Letters 0
Product Types oral-capsule, spray, bioregulators

Company Overview

Integrative Peptides was founded in 2018 by Dr. Kent Holtorf, M.D. (UCLA School of Medicine). Holtorf simultaneously operates the Holtorf Medical Group, a chain of 22+ corporate medical centers. This creates a notable dual role — he owns both a supplement company and a medical practice chain that recommends those products to patients. While not illegal, this is a structural conflict of interest that consumers should be aware of.

Products & Pricing

The product line includes oral capsules and sprays covering a wide range of peptides:

ProductFormatPriceKey Ingredient
BPC-157 Pure60 capsules~$150BPC-157
TB4-FragCapsules~$130TB-500 fragment
KPVCapsules~$120KPV tripeptide
CerebroPepCapsules~$140Cerebrolysin-related peptide
Thymogen Alpha-1Capsules~$130Thymosin Alpha-1
Bioregulator lineVarious$60–$150Various short peptide bioregulators

All products are positioned as dietary supplements. Pricing is at the premium end of the oral peptide market.

Transparency Assessment

Score: 40/100 — Significant gaps. The company claims ≥99% purity and third-party testing, but COAs are not publicly displayed on the website and the testing laboratory is not named. For a company selling premium-priced peptides, the absence of publicly verifiable lab reports is a meaningful concern. Consumers must take the company’s word on quality without independent verification.

Testing & Quality

Score: 55/100 — Claims third-party testing but doesn’t provide the verification needed to confirm it. Without named labs, publicly accessible COAs, or batch-specific documentation, the testing claims cannot be independently validated.

Pricing Assessment

Score: 35/100 — Premium pricing ($150 for 60 capsules of BPC-157) in a market where the cost of raw peptide ingredients is estimated at $10–25 per bottle. While markup is expected in supplements, 80%+ gross margins combined with unverified quality claims represent poor consumer value.

Regulatory Standing

No FDA warning letters have been identified. However, legal experts (Holt Law, Frier Levitt) have noted that oral BPC-157 supplements are “just as illegal as the injectable version” — BPC-157 is a synthetic peptide, not a recognized dietary ingredient under DSHEA, and no New Dietary Ingredient Notification (NDIN) has been filed by Integrative Peptides or any other BPC-157 vendor. The FDA has simply not yet chosen to enforce against oral BPC-157 supplement sellers at scale.

Customer Experience

No BBB listing found. No Trustpilot profile. Minimal independent Reddit presence. Most content about the brand comes from the founder’s own marketing channels. One review on Professional Supplement Center reported severe illness within 45 minutes of taking a product (dizziness, vomiting, headache) — a single report, but one that lacks any company response.

Red Flags

  1. Founder dual role: Owns both the supplement company and a medical practice chain recommending the products
  2. No public COAs: Claims testing but provides no verifiable documentation
  3. Testing lab unnamed: Cannot independently verify quality claims
  4. Premium pricing without transparency: High prices demand high transparency, which is absent
  5. NDI notification gap: Products may not comply with DSHEA requirements
  6. Minimal independent reviews: Very little third-party feedback to assess quality

The Bottom Line

Integrative Peptides occupies a concerning middle ground — premium prices and physician branding suggest quality, but the lack of publicly verifiable testing documentation doesn’t support that suggestion. The structural conflict between operating a supplement company and a medical practice that recommends those supplements warrants consumer awareness. Until the company publishes named-lab, batch-specific COAs, the quality claims remain unverifiable.